C2H7NO 61.08

Ethanol, 2-amino-.
2-Aminoethanol [141-43-5].

Packaging and storage— Preserve in tight, light-resistant containers.

USP Reference standards 11—
USP Monoethanolamine RS .

Identification, Infrared Absorption 197F.

Specific gravity 841: between 1.013 and 1.016.

Distilling range, Method II 721— Not less than 95% of it distills between 167 and 173, a correction factor of 0.052 per mm being applied as necessary.

Organic volatile impurities, Method I 467: meets the requirements.

(Official until July 1, 2008)

Residue on ignition 281: not more than 0.1%.

Assay— Accurately weigh a glass-stoppered weighing bottle containing 25 mL of water. Add 1 g of Monoethanolamine, and weigh. Transfer to a suitable flask, add a mixed indicator of 5 parts bromocresol green TS and 6 parts methyl red TS for a total of approximately 11 parts of solution, mix, and titrate with 0.5 N hydrochloric acid VS. Each mL of 0.5 N hydrochloric acid is equivalent to 30.54 mg of C2H7NO.

Expert Committee : (EM105) Excipient Monographs 1

USP31–NF26 Page 1178

Phone Number : 1-301-816-8335